Loading Events

« All Events

  • This event has passed.

Research meeting: Hans Fredrik Sunde

November 7 @ 1:00 pm - 2:00 pm

Hans Fredrik Sunde will present a talk titled “Understanding indirect assortative mating and its intergenerational consequences”. Hans Fredrik is a postdoc at the Centre for Fertility and Health (Norwegian Institute of Public Health), where he investigates partner similarity and its consequences for social differences, mental health, and genetic methodology. He has a background in psychology and is currently on a research stay in Amsterdam.

Summary/Abstract: Partners tend to have similar levels of education. Previous studies indicate that this is likely due to some form of indirect assortative mating but there is not a consistent understanding of this process. Understanding indirect assortment is crucial for resolving the role of nature and nurture in education. We attribute previous inconsistencies to idiosyncratic models and inconsistent use of relevant terms. In this paper, we develop a new framework for understanding indirect assortative mating and provide updated definitions of key terms. We then develop a model (the iAM-ACE-model) that can use partners of twins and siblings to distinguish the degree of assortment on genetic, social, and individual characteristics. We also expand this model to include children of twins and siblings (the iAM-COTS model), allowing us to explain parent-offspring similarity while accounting for indirect assortative mating and gene-environment correlations. We apply the models on educational attainment using 1,529,144 individuals in 209,792 extended families from Norwegian registry data and the Norwegian Twin Registry. The analysis suggests that partner similarity in educational attainment can be explained by strong assortment on sibling-shared environmental factors, with only moderate assortment on genetic factors. The implied genotypic correlation between partners (r = .33) is comparable to earlier studies, and higher than expected under direct assortment. Most of the parent-offspring correlation (r = .33) was attributable to passive genetic transmission (62%), with the rest attributable to passive environmental transmission (23%) and direct phenotypic transmission (15%). Environmental transmission was estimated lower in alternative models that assumed direct assortment, but these did not fit the data well (pre-print link: https://doi.org/10.1101/2024.06.21.600029).

Details

Date:
November 7
Time:
1:00 pm - 2:00 pm

Organiser

Genetics Network Amsterdam
View Organiser Website

Venue

VU Amsterdam
Amsterdam,+ Google Map
Share This