I received my Undergraduate and Masters training from the University of Southampton (England) and my PhD from the KU Leuven (Belgium). Throughout this training I began to specialise in the preclinical phase of Alzheimer’s disease, particularly from a genetic and transcriptomic perspective. After a one-year postdoc at the Karolinksa Institutet (Sweden), I moved to Amsterdam where I am now both a data manager and post-doctoral researcher in the group of Professor Frederik Barkhof, in the Department of Radiology and Nuclear Medicine at the Amsterdam UMC. My data manager role focusses on integrating, harmonising, maintaining, and enhancing/enlarging our large pan-European preclinical Alzheimer’s Disease consortium (AMYPAD), whereas my postdoctoral researcher role focusses on understanding the polygenic architecture to Alzheimer’s disease endophenotypes, such as brain amyloid accumulation. I have always focussed on understanding early pathogenesis and risk factors of Alzheimer’s disease using various techniques, where my goal has been, and continues to be, to understand these early changes to allow for improved risk stratification and risk prediction to allow for intervention prior to symptom onset.